Fluorescent Sarcosine Detection Kit

Part # 6024: Enzyme Mix, 1 Vial (-20C), Part # 3056: Standard Curve Diluent, 40mL (2-8C), Part # 4023: Sarcosine Detection Reagent, 1 Vial (2-8C), Part # 7021: Sarcosine Standard, 1 Vial (2-8C)

Sarcosine is natural amino acid that is an important intermediate in the metabolism of choline. Sarcosine is an important component of proteins and plays a significant role in metabolic processes of living cells as a source of serine, creatine, purines and glutathione etc. Sarcosine is present in such food sources like legumes, eggs, ham, turkey etc. It is used in a variety of industrial applications such as manufacturing of tooth paste and biodegradable surfactants. Sarcosine was recently reported to activate prostate cancer cells and is indicated as a possible marker for prostate cancer progression to metastasis. It is also used in adjunctive treatment for Schizophrenia and depression. This kit provides a reliable, sensitive fluorometric assay for quantifying sarcosine in biological samples. A non-fluorescent detection reagent, is reduced via an enzyme-coupled reaction in the presence of sarcosine to yield a fluorescent product. The kit is suitable for use with serum, cells, and tissue extracts.