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Chlorination and Oxidation detection Kit

Can monitor multiple time points to follow kinetics., One-step, no wash assay., Adaptable for High Throughput format., Highly Sensitive.

Product Specifications

Label

ICT

Type

Metabolic Assays

Detection Method

Fluorescence plate reader

Assay Protocol

https://cdn.shopify.com/s/files/1/0512/5793/4009/files/MPOHOCL_Protocol_2.pdf?v=1693431067

Components

Part# 4007: Detection Reagent, 1 Vial ('-20C), Part# 3002: 10X Assay Buffer, 60mL (2-8C), Part# 3012: Hydrogen Peroxide, 1000µL of a Stabilized 3% Solution (2-8C), Part# 6015: Myeloperoxidase, 1 Vial at 30Units/mL (2-8C), Part# 4011: APF, 1 Vial (2-8C)

Shipping Conditions

Ships overnight (domestic), International Priority Shipping

Storage Temperature

2-8°C

Target Description

Fluoro MPOHOCL uses a chlorination activity protocol that utilizes a non-fluorescent detection reagent,, APF, which is converted to its fluorescent analog in the presence of HOCl. The kit is used for detection of, MPO chlorination activity in neutrophils and macrophages, as Well as detection of PMN infiltration in tissue, samples (inflammation and innate host defense mechanisms). MPO chlorination activ- ity been implicated, in acute and chronic manifestations of cardiovascular disease and acute and chronic inflammatory, disorders due to chlorination tissue damage.

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