Recombinant Mouse IL-34

Interleukin-34 (IL-34) is a homodimeric cytokine recognized by colony-stimulating factor 1 receptor (CSF-1R). IL-34 is involved in the survival, proliferation, and differentiation of mononuclear phagocytes. Mouse IL-34 Recombinant Protein is purified interleukin-15 produced in yeast.

Product Specifications

Synonyms

Mouse ; IL-34

Label

ICT

Type

Recombinant Protein

Source

Yeast

Sequence

NENLEIWTLT QDKECDLTGY LRGKLQYKNR LQYMKHYFPI NYRIAVPYEG VLRVANITRL QKAHVSEREL RYLWVLVSLN ATESVMDVLL EGHPSWKYLQ EVQTLLENVQ RSLMDVEIGP HVEAVLSLLS TPGLSLKLVR PKALLDNCFR VMELLYCSCC KQSPILKWQD CELPRLHPHS PGSLMQCTAT NVYPLSRQTP TSLPGSPSSS HGSLP (215)

Assay Protocol

The Human IL-1 beta protein can be used in cell culture, as an IL-1 beta ELISA Standard, and as a Western Blot Control.

Form

Lyophilized

Shipping Conditions

Shipping: Ships at ambient temperature, Ships overnight (domestic), International Priority Shipping

Storage Temperature

-20°C

Notes

20% discount

Calculated Molecular Weight

24.6 kDa

Target Description

Interleukin-34 (IL-34) is a homodimeric cytokine identified by high throughput screening of human recombinant secreted factors. It contains no known conserved domains and has no sequence homology with other cytokines. IL-34 is recognized by colony-stimulating factor 1 receptor (CSF-1R). CSF-1R also binds CSF-1, also called macrophage colony-stimulating factor (M-CSF). Both IL-34 and CSF-1 are involved in the survival, proliferation, and differentiation of mononuclear phagocytes, including monocytes, macrophages, dendritic cells, Langerhans cells, microglia, and osteoclasts.