TNP
Product Specifications
UNSPSC Description
TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 µM and 10.2 µM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes[1].
Target Antigen
IPK Superfamily
Type
Reference compound
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IP3K_Inhibitor.html
Purity
99.29
Solubility
DMSO : 37.5 mg/mL (ultrasonic)
Smiles
FC(C1=CC(CNC2=NC(NCC3=CC=C([N+]([O-])=O)C=C3)=C4N=CNC4=N2)=CC=C1)(F)F
Molecular Weight
443.38
References & Citations
[1]Chang YT, et al. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem. 2002 Sep 2;3(9):897-901.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-110079/TNP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110079/TNP-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
519178-28-0
Available Sizes
Curated Selection
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