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ω-Conotoxin CVIE

Product Specifications

UNSPSC Description

ω-Conotoxin CVIE is a voltage-gated Ca2+ channel (Ca v 2.2) selective inhibitor [1].

Target Antigen

Calcium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](N)CSSC[C@H](NC1=O)C(N[C@H](C(NCC(N[C@H]2CO)=O)=O)[C@@H](C)O)=O)N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CSSC[C@H](NC3=O)C(N)=O)=O)CC(O)=O)=O)CC4=CC=C(O)C=C4)=O)CO)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(NCC(N[C@H]3CCCNC(N)=N)=O)=O)CO)=O)CCCNC(N)=N)=O)=O)CO)=O)C)=O)=O)CCCCN)=O)=O)CCCCN

Molecular Weight

2638.99

References & Citations

[1]Berecki G, et al. Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels. Br J Pharmacol. 2014 Jul;171(13):3313-27.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Frequently Asked Questions

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