Anti-Mouse TCR gamma/delta Antibody (UC7-13D5)

Anti-Mouse TCR gamma/delta Antibody (UC7-13D5) is an anti-mouse TCR gamma/delta IgG monoclonal antibody. Anti-Mouse TCR gamma/delta Antibody (UC7-13D5) can enter the blood-brain barrier. Anti-Mouse TCR gamma/delta Antibody (UC7-13D5) effectively depletes γδ T cells and reduces macrophage and neutrophil infiltration. Anti-Mouse TCR gamma/delta Antibody (UC7-13D5) can reduce the immune response of transplants. Anti-Mouse TCR gamma/delta Antibody (UC7-13D5) can be used for researches on inflammation conditions, virus infection and cancer such as arthritis, JHM virus and breast cancer[1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

CD3

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anti-mouse-tcr-gamma-delta-antibody-uc7-13d5.html

Purity

95.0

Solubility

H2O

Smiles

[Anti-MouseTCRgamma/deltaAntibody(UC7-13D5)]

Molecular Weight

(150 kDa)

References & Citations

[1]Dandekar AA, et al. Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirus. J Virol. 2005 Aug;79 (15) :9388-96.|[2]Bouchareychas L, et al. γδTCR regulates production of interleukin-27 by neutrophils and attenuates inflammatory arthritis. Sci Rep. 2018 May 15;8 (1) :7590.|[3]Inatsuka C, et al. Gamma delta T cells are activated by polysaccharide K (PSK) and contribute to the anti-tumor effect of PSK. Cancer Immunol Immunother. 2013 Aug;62 (8) :1335-45.|[4]Sakai T, et al. Host intestinal intraepithelial gamma delta T lymphocytes present during acute graft-versus-host disease in mice may contribute to the development of enteropathy. Eur J Immunol. 1995 Jan;25 (1) :87-91.