Saponarin
Saponarin is an orally active flavonoid compound. Saponarin can be isolated from Gypsophila trichotoma. Saponarin inhibits ERK/p38, NF-κB and MAPK phosphorylation and activates AMPK. Saponarin reduces IL-1β and COX-2. Saponarin has antioxidant, anti-inflammatory, hepatoprotective, hypoglycemic and hypotensive effects. Saponarin improves sleep disorders[1][2][3][4][5][6][7].
Product Specifications
CAS Number
20310-89-8
UNSPSC
12352005
Hazard Statement
H315, H319
Target
AMPK; COX; Interleukin Related; NF-κB; p38 MAPK; PERK
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation; MAPK/ERK Pathway; NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/saponarin.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C([C@H]5[C@@H]([C@H]([C@@H]([C@@H](CO)O5)O)O)O)C(O)=C13
Molecular Formula
C27H30O15
Molecular Weight
594.52
Precautions
H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; IL-1
Available Sizes
Frequently Asked Questions
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