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GSD-16-24

GSD-16-24 is a lead compound that binds directly to the C-terminal IDR of α-syn monomers and fibrils, thereby preventing fibrils from binding to the receptor. GSD-16-24 can be used in Parkinson's research[1].

Product Specifications

UNSPSC

12352005

Target

α-synuclein

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/gsd-16-24.html

Smiles

CN1CCN(CC1)C2=CC3=C(C=C(C=C3)COC(NC4=CC=CC(C(NO)=O)=C4)=O)C=C2

Molecular Formula

C24H26N4O4

Molecular Weight

434.49

References & Citations

[1]Zhang S, et al. Inhibitor Development for α-Synuclein Fibril's Disordered Region to Alleviate Parkinson's Disease Pathology. J Am Chem Soc. 2024 Oct 16;146 (41) :28282-28295.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α-synuclein Aggregation

Frequently Asked Questions

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