GSD-16-24
GSD-16-24 is a lead compound that binds directly to the C-terminal IDR of α-syn monomers and fibrils, thereby preventing fibrils from binding to the receptor. GSD-16-24 can be used in Parkinson's research[1].
Product Specifications
UNSPSC
12352005
Target
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsd-16-24.html
Smiles
CN1CCN(CC1)C2=CC3=C(C=C(C=C3)COC(NC4=CC=CC(C(NO)=O)=C4)=O)C=C2
Molecular Formula
C24H26N4O4
Molecular Weight
434.49
References & Citations
[1]Zhang S, et al. Inhibitor Development for α-Synuclein Fibril's Disordered Region to Alleviate Parkinson's Disease Pathology. J Am Chem Soc. 2024 Oct 16;146 (41) :28282-28295.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation
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