Rolipram
Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC50s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
Product Specifications
CAS Number
[61413-54-5]
Product Name Alternative
(R, S) -Rolipram; (±) -Rolipram; ZK 62711
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; HIV; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Rolipram.html
Purity
99.45
Solubility
DMSO : ≥ 41 mg/mL|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NCC(C2=CC=C(OC)C(OC3CCCC3)=C2)C1
Molecular Formula
C16H21NO3
Molecular Weight
275.35
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16900/Rolipram-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16900/Rolipram-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PDE4
Available Sizes
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