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SP1 antibody

Product Specifications

Background

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Synonyms

Transcription factor Sp1|SP1|TSFP1

Gene ID

6667

UniProt

P08047

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Transcription factor Sp1

Target

SP1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

90 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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