Gestodene

Gestodene (SHB 331; WL 70) is a progestin-based contraceptive. Gestodene is a click chemistry reagent. It contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an azide group[1][2].

Product Specifications

CAS Number

[60282-87-3]

Product Name Alternative

SHB 331; WL 70

UNSPSC

12352211

Hazard Statement

H361

Target

Progesterone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/Gestodene.html

Purity

99.90

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CC[C@@]1([C@]2(O)C#C)[C@](C=C2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@@]3([H])CC4)([H])CC1

Molecular Formula

C21H26O2

Molecular Weight

310.43

Precautions

H361

References & Citations

[1]Spona, J. and J. Huber, Pharmacological and endocrine profiles of gestodene. Int J Fertil, 1987. 32 Suppl: p. 6-14.|[2]Pollow, K., et al., Lack of binding of gestodene to estrogen receptor in human breast cancer tissue. Eur J Cancer, 1990. 26 (5) : p. 608-10.