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CCT031374 (hydrobromide)

CCT 031374 hydrobromid is a potent inhibitor of β-catenin/transcription factor (TCF) complex signaling. CCT031374 inhibits TCF-dependent transcription of genes of Wnt signaling pathway. CCT 031374 has antitumor activity[1].

Product Specifications

CAS Number

1219184-91-4

UNSPSC

12352005

Target

Wnt; β-catenin

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cct031374-hydrobromide.html

Purity

98.08

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)CN3C4=NCCN4C5=CC=CC=C35.[H]Br

Molecular Formula

C23H20BrN3O

Molecular Weight

434.33

References & Citations

[1]Ewan K, et al. A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Res. 2010 Jul 15;70 (14) :5963-73.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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