Anti-Mouse IL-1a Antibody (ALF-161)

Anti-Mouse IL-1a Antibody (ALF-161) is an anti-mouse IL-1a IgG1 monoclonal antibody. Anti-Mouse IL-1a Antibody (ALF-161) can inhibit CD8+ T cell response by blocking IL-1a signaling. Anti-Mouse IL-1a Antibody (ALF-161) can reversibly transform myeloid cell expansion and improve T cell function. Anti-Mouse IL-1a Antibody (ALF-161) can be used for researches on immune response and cancer such as breast cancer[1][2].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-il-1a-antibody-alf-161.html

Purity

95.0

Solubility

H2O

Smiles

[Anti-MouseIL-1aAntibody(ALF-161)]

Molecular Weight

(150 kDa)

References & Citations

[1]Kumar SRP, et al. TLR9-independent CD8+ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling. Mol Ther. 2024 Feb 7;32 (2) :325-339.|[2]Allen BM, et al. Systemic dysfunction and plasticity of the immune macroenvironment in cancer models. Nat Med. 2020 Jul;26 (7) :1125-1134.