Sodium 4-phenylbutyrate (Standard)
Product Specifications
UNSPSC Description
Sodium 4-phenylbutyrate (Standard) is the analytical standard of Sodium 4-phenylbutyrate. This product is intended for research and analytical applications. Sodium 4-phenylbutyrate (4-PBA sodium) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research[1].
Target Antigen
Apoptosis; Autophagy; HDAC
Type
Reference Standards
Related Pathways
Apoptosis;Autophagy;Cell Cycle/DNA Damage;Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sodium-4-phenylbutyrate-standard.html
Smiles
O=C(O[Na])CCCC1=CC=CC=C1
Molecular Weight
186.18
References & Citations
[1]Chang TH, et al. Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. Clin Cancer Res. 2002 Apr;8(4):1206-12.|[2]Frouco G, et, al. Sodium phenylbutyrate abrogates African swine fever virus replication by disrupting the virus-induced hypoacetylation status of histone H3K9/K14. Virus Res. 2017 Oct 15;242:24-29.|[3]Park HJ, et al. 4-Phenylbutyric acid protects against lipopolysaccharide-induced bone loss by modulating autophagy in osteoclasts. Biochem Pharmacol. 2018 May;151:9-17.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15654R/Sodium-4-phenylbutyrate-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15654R/
CAS Number
1716-12-7
Available Sizes
Curated Selection
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