Sodium 4-phenylbutyrate (Standard)

Sodium 4-phenylbutyrate (Standard) is the analytical standard of Sodium 4-phenylbutyrate. This product is intended for research and analytical applications. Sodium 4-phenylbutyrate (4-PBA sodium) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research[1].

Product Specifications

CAS Number

[1716-12-7]

Product Name Alternative

4-PBA (sodium) (Standard) ; 4-Phenylbutyric acid (sodium) (Standard) ; Benzenebutyric acid (sodium) (Standard)

UNSPSC

12352005

Target

Apoptosis; Autophagy; HDAC; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sodium-4-phenylbutyrate-standard.html

Smiles

O=C(O[Na])CCCC1=CC=CC=C1

Molecular Formula

C10H11NaO2

Molecular Weight

186.18

References & Citations

[1]Chang TH, et al. Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. Clin Cancer Res. 2002 Apr;8 (4) :1206-12.|[2]Frouco G, et, al. Sodium phenylbutyrate abrogates African swine fever virus replication by disrupting the virus-induced hypoacetylation status of histone H3K9/K14. Virus Res. 2017 Oct 15;242:24-29.|[3]Park HJ, et al. 4-Phenylbutyric acid protects against lipopolysaccharide-induced bone loss by modulating autophagy in osteoclasts. Biochem Pharmacol. 2018 May;151:9-17.