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Histone H2A.X (Phospho Thr120) rabbit pAb

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]

Product Name Alternative

H2AFX; H2AX; Histone H2A.x; H2a/x

UniProt

P16104

Swiss Prot

P16104

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic Peptide of Histone H2A.X (Phospho Thr120)

Target

Histone H2A.X

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Dilution

WB: 1:1000-2000

Buffer

-20°C/1 year

Molecular Weight

15kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

15kD

Fragment

IgG

Subcellular Location

Nucleus . Chromosome .

Other Product Names

H2AFX; H2AX; Histone H2A.x; H2a/x

Gene ID (Human)

3014

Available Sizes

Frequently Asked Questions

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