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Poly-L-ornithine (hydrochloride) (MW 15000-30000)

Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1) . Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases[1][2][3][4][5].

Product Specifications

CAS Number

26982-21-8

Product Name Alternative

L-Ornithine homopolymer (hydrochloride) (MW 15000-30000)

UNSPSC

12352200

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Endocrinology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/poly-l-ornithine-hydrochloride-mw-15000-30000.html

Solubility

H2O : 50 mg/mL (ultrasonic; warming)

Smiles

CC([C@@H](N)CCCNC)=O.[n].[x].Cl

Molecular Formula

(C5H12N2O2) n.xHCl

Molecular Weight

15000-30000

References & Citations

[1]Abbah SA, et al. In vivo bioactivity of rhBMP-2 delivered with novel polyelectrolyte complexation shells assembled on an alginate microbead core template. J Control Release. 2012 Sep 10;162 (2) :364-72.|[2]McQuilling JP, et al. New alginate microcapsule system for angiogenic protein delivery and immunoisolation of islets for transplantation in the rat omentum pouch. Transplant Proc. 2011 Nov;43 (9) :3262-4.|[3]Somo SI, et al. Dual Crosslinking of Alginate Outer Layer Increases Stability of Encapsulation System. Front Chem. 2020 Nov 12;8:575278. |[4]Kamiya Y, et al. Preparation and Evaluation of PEGylated Poly-L-ornithine Complex as a Novel Absorption Enhancer. Biol Pharm Bull. 2017;40 (2) :205-211.|[5]Khan AN, et al. Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases. J Biol Chem. 2006 Apr 28;281 (17) :11702-11.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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