WRN inhibitor 8
Product Specifications
UNSPSC Description
WRN inhibitor 8 (Example 224) is a WRN helicase inhibitor with IC50 value of 48 nM. WRN inhibitor 8 can be used in cancer research[1].
Target Antigen
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wrn-inhibitor-8.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CS(/C=C/[C@H](C1CC1)NC(C(C(OC2=CC=CC=C2)=N3)=CN=C3C(F)(C4CC4)F)=O)(=O)=O
Molecular Weight
463.50
References & Citations
[1]Shota Kikuchi, et al. Pharmaceutical compositions comprising wrn helicase inhibitors. WO2024010782A1. 2024-01-11.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160859/WRN-inhibitor-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160859/WRN-inhibitor-8-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3026502-95-1
Available Sizes
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