WRN inhibitor 8
WRN inhibitor 8 is an inhibitor of WRN helicase with an IC50 value of 48 nM. WRN inhibitor 8 can inhibit the proliferation of tumor cells and be used in the study of cancer[1].
Product Specifications
CAS Number
[3026502-95-1]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wrn-inhibitor-8.html
Purity
98.07
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CS(/C=C/[C@H](C1CC1)NC(C(C(OC2=CC=CC=C2)=N3)=CN=C3C(F)(C4CC4)F)=O)(=O)=O
Molecular Formula
C22H23F2N3O4S
Molecular Weight
463.50
References & Citations
[1]Shota Kikuchi, et al. Pharmaceutical compositions comprising wrn helicase inhibitors. WO2024010782A1. 2024-01-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
ABC-X3279 1 Vial
Xpress™ Human TRPM7 Over-expressing Stable Cell Line
Sign In for Pricing
View Details NBP3-14191AF647 0.1 mL
Mouse Monoclonal SURF5 Antibody (PCRP-MED22-2A7) [Alexa Fluor 647]
Sign In for Pricing
View Details 
VAng-Yyj3831-1mgEcoli 1 mg (E. coli)
Recombinant Mycobacterium Ulcerans rpsG Protein (aa 1-156)
Sign In for Pricing
View Details 218946-01 20 µL
FABP5 (Fatty Acid Binding Protein 5, E-FABP, EFABP, PA-FABP, PAFABP, KFABP) discontinued
Sign In for Pricing
View Details 218946-02 100 µL
FABP5 (Fatty Acid Binding Protein 5, E-FABP, EFABP, PA-FABP, PAFABP, KFABP) discontinued
Sign In for Pricing
View Details 