WRN inhibitor 8
WRN inhibitor 8 is an inhibitor of WRN helicase with an IC50 value of 48 nM. WRN inhibitor 8 can inhibit the proliferation of tumor cells and be used in the study of cancer[1].
Product Specifications
CAS Number
[3026502-95-1]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wrn-inhibitor-8.html
Purity
98.07
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CS(/C=C/[C@H](C1CC1)NC(C(C(OC2=CC=CC=C2)=N3)=CN=C3C(F)(C4CC4)F)=O)(=O)=O
Molecular Formula
C22H23F2N3O4S
Molecular Weight
463.50
References & Citations
[1]Shota Kikuchi, et al. Pharmaceutical compositions comprising wrn helicase inhibitors. WO2024010782A1. 2024-01-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
C0305M 100 Tests
BeyoColorTM Mycoplasma Colorimetric LAMP Assay Kit
Sign In for Pricing
View Details 
MBS1423169-01 0.02 mg (E-Coli)
Recombinant Caenorhabditis elegans LIM domain-containing protein pin-2 (pin-2)
Sign In for Pricing
View Details MBS1423169-02 0.02 mg (Yeast)
Recombinant Caenorhabditis elegans LIM domain-containing protein pin-2 (pin-2)
Sign In for Pricing
View Details 
MBS1423169-03 0.1 mg (E-Coli)
Recombinant Caenorhabditis elegans LIM domain-containing protein pin-2 (pin-2)
Sign In for Pricing
View Details MBS1423169-04 0.1 mg (Yeast)
Recombinant Caenorhabditis elegans LIM domain-containing protein pin-2 (pin-2)
Sign In for Pricing
View Details MBS1423169-05 0.02 mg (Baculovirus)
Recombinant Caenorhabditis elegans LIM domain-containing protein pin-2 (pin-2)
Sign In for Pricing
View Details