WRN inhibitor 8
WRN inhibitor 8 is an inhibitor of WRN helicase with an IC50 value of 48 nM. WRN inhibitor 8 can inhibit the proliferation of tumor cells and be used in the study of cancer[1].
Product Specifications
CAS Number
[3026502-95-1]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wrn-inhibitor-8.html
Purity
98.07
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CS(/C=C/[C@H](C1CC1)NC(C(C(OC2=CC=CC=C2)=N3)=CN=C3C(F)(C4CC4)F)=O)(=O)=O
Molecular Formula
C22H23F2N3O4S
Molecular Weight
463.50
References & Citations
[1]Shota Kikuchi, et al. Pharmaceutical compositions comprising wrn helicase inhibitors. WO2024010782A1. 2024-01-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV728448 1.0 µg DNA
HNRNPA1P25 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details 043552-FITC 200 µL
UBP46, CT (USP46, Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46) (FITC) discontinued
Sign In for Pricing
View Details 
GTR15226053 1 Vial
Lentiviral mouse Vmn1r148 shRNA (UAS) - Lentiviral mouse Vmn1r148 shRNA (UAS, GFP) (100)
Sign In for Pricing
View Details 
bs-8048R-APC-Cy7 100 µL
KLHL21 Polyclonal Antibody, APC-Cy7 Conjugated
Sign In for Pricing
View Details