11-Deoxy Prostaglandin E2
11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions[1][2].
Product Specifications
CAS Number
35536-53-9
UNSPSC
12352211
Hazard Statement
H302, H360
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/11-deoxy-prostaglandin-e2.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
CCCCC[C@@H](/C=C/[C@@H](CCC1=O)[C@H]1C/C=C\CCCC(O)=O)O
Molecular Formula
C20H32O4
Molecular Weight
336.47
Precautions
H302, H360
References & Citations
[1]Holt MC, et al. Improved homology modeling of the human & rat EP4 prostanoid receptors. BMC Mol Cell Biol. 2019 Aug 27;20 (1) :37.|[2]Ungrin MD, et al. Key structural features of prostaglandin E (2) and prostanoid analogs involved in binding and activation of the human EP (1) prostanoid receptor. Mol Pharmacol. 2001 Jun;59 (6) :1446-56.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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