Bromodiphenhydramine (hydrochloride)

Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research[1][2][3].

Product Specifications

CAS Number

[1808-12-4]

Product Name Alternative

Ambodryl (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302

Target

Bacterial; Histamine Receptor

Type

Reference compound

Related Pathways

Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bromodiphenhydramine-hydrochloride.html

Purity

97.34

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

BrC1=CC=C(C(C2=CC=CC=C2)OCCN(C)C)C=C1.[H]Cl

Molecular Formula

C17H21BrClNO

Molecular Weight

370.71

Precautions

H302

References & Citations

[1]MOLINA EB. [A new antihistaminic, bromodiphenhydramine hydrochloride, in the control of cutaneous allergies]. Sem Med. 1960 Jul 11;117:151-2. Spanish. |[2]Dastidar SG, et al. Antibacterial activity of ambodryl and benadryl. J Appl Bacteriol. 1976 Oct;41 (2) :209-14.|[3]Ray S, et al. Studies on synergism between penicillins and ambodryl (bromodiphenhydramine HCl), an antihistamine with antimicrobial property. Indian J Exp Biol. 1990 Mar;28 (3) :253-8.