Gimatecan
Product Specifications
UNSPSC Description
Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity[1].
Target Antigen
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gimatecan.html
Purity
99.28
Solubility
DMSO : 33.33 mg/mL (ultrasonic;warming;adjust pH to 10 with NaOH;heat to 60°C)
Smiles
CC(C)(C)O/N=C/C1=C2C(C(N3C2)=CC([C@@]4(O)CC)=C(COC4=O)C3=O)=NC5=CC=CC=C15
Molecular Weight
447.48
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0063/Gimatecan-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0063/Gimatecan-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
292618-32-7
Available Sizes
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