Gimatecan

Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity[1].

Topoisomerase

Reference compound

Cell Cycle/DNA Damage

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/gimatecan.html

99.28

DMSO : 33.33 mg/mL (ultrasonic;warming;adjust pH to 10 with NaOH;heat to 60°C)

CC(C)(C)O/N=C/C1=C2C(C(N3C2)=CC([C@@]4(O)CC)=C(COC4=O)C3=O)=NC5=CC=CC=C15

447.48

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-B0063/Gimatecan-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-B0063/Gimatecan-SDS-MedChemExpress.pdf

Phase 2

292618-32-7