Amino-PEG4-alcohol
Product Specifications
UNSPSC Description
Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amino-peg4-alcohol.html
Purity
99.73
Solubility
DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)
Smiles
NCCOCCOCCOCCO
Molecular Weight
193.24
References & Citations
[1]Nello Mainolfi, et al. Protein degraders and uses thereof. WO2019060742A1.|[2]Miller MA, et al. Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation. ACS Nano. 2018 Dec 26;12(12):12814-12826.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W008005/Amino-PEG4-alcohol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W008005/Amino-PEG4-alcohol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
86770-74-3
Available Sizes
Curated Selection
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