C-7280948
C-7280948 is a selective and potent protein methyltransferase1 (PRMT1) inhibitor with an IC50 value of 12.75 μM[1].
Product Specifications
CAS Number
[587850-67-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/C-7280948.html
Purity
99.91
Solubility
DMSO : ≥ 38 mg/mL
Smiles
O=S(C1=CC=C(N)C=C1)(NCCC2=CC=CC=C2)=O
Molecular Formula
C14H16N2O2S
Molecular Weight
276.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Bissinger EM, et al. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bioorg Med Chem. 2011 Jun 15;19 (12) :3717-3731.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT1
Available Sizes
Curated Selection
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