PROTAC SOS1 degrader-9
PROTAC SOS1 degrader-9 (Compd 10) is a PROTAC-based SOS1 degrader (Red: SOS1 Ligand , Black: linker (HY-W056267), Blue: E3 ligase ligand (HY-161639) ).
Product Specifications
CAS Number
3036155-21-9
UNSPSC
12352005
Target
PROTACs; Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-sos1-degrader-9.html
Smiles
N#CC1=C(C)C([C@@H](C)NC2=NN=C(C)C3=C2C=C(N4CCN(C(C5CCN(CC6CCC7(CCN(C(C8=CC(N9CCC(NC9=O)=O)=C(C)C=C8)=O)CC7)CC6)CC5)=O)CC4)N=C3)=CC=C1
Molecular Formula
C51H63N11O4
Molecular Weight
894.12
References & Citations
[1]Zhengqing Ye, et al. Sos1 protein degradation agent and use thereof. Patent. WO2024083257A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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