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[Pyr1]-Apelin-13

[Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist.

Product Specifications

CAS Number

217082-60-5

Product Name Alternative

[pGlu1]-Apelin-13

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Apelin Receptor (APJ)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/-Pyr1-Apelin-13.html

Purity

99.69

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@H]1CCC(N1)=O)N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCCN)C(NCC(N3[C@@H](CCC3)C(N[C@@H](CCSC)C(N4[C@@H](CCC4)C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O

Molecular Formula

C69H108N22O16S

Molecular Weight

1533.80

Precautions

H302, H315, H319, H335

References & Citations

[1]Serpooshan V, et al. [Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction. Biomaterials. 2015 Jan;37:289-98.|[2]Hajimashhadi Z, et al. Chronic administration of [Pyr1] apelin-13 attenuates neuropathic pain after compression spinal cord injury in rats. Neuropeptides. 2017 Feb;61:15-22.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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