BPC 157

BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over) stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems[1][2][3].

Product Specifications

CAS Number

[137525-51-0]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

FAK; JAK

Type

Peptides

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bpc-157.html

Purity

99.86

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O=C([C@H]1N(CCC1)C([C@H](CCC(O)=O)NC(CN)=O)=O)N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C62H98N16O22

Molecular Weight

1419.54

Precautions

H302, H315, H319, H335

References & Citations

[1]Sikiric P, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011;17 (16) :1612-1632.|[2]Klicek R, et al. Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol. 2013;64 (5) :597-612.|[3]Desgagné M, et al., Development of Macrocyclic Neurotensin Receptor Type 2 (NTS2) Opioid-Free Analgesics. Angew Chem Int Ed Engl. 2024 Nov 18;63 (47) :e202405941.