GMP Human IL-4 Protein
Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells) . In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.
Product Specifications
Background
Specifications
Accession Number
P05112-1
Expression Region
His 25 - Ser 153
Host
HEK293
Target
IL-4
Conjugation
Unconjugated
Tag
Native
Stability
Endotoxin
10 EU/mg
Purity
95%
Format
Powder-GMP
Buffer
PBS, pH7.4
Molecular Weight
15.0 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Blue ice
Storage Conditions
-20°C
Package Size
50ug*200
Host or Source
HEK293
Species
Human
Protein ID
P05112-1
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