Monoclonal Anti-Whitlow 218 linker Antibody, Rabbit IgG (P3C09)
Monoclonal Anti-Whitlow 218 linker Antibody, Rabbit IgG (P3C09) is a monoclonal antibody recombinantly expressed from HEK293 cells, which provides higher batch consistency and long term security of supply.
Product Specifications
Background
The whitlow/218 linker, with the sequence GSTSGSGKPGSGEGSTKG, is a commonly used synthetic peptide linker. Whitlow/218 linker often leveraged to connect the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The scFv containing the 218 linker showed reduced aggregation and was found to be more stable to proteolysis in vitro.
Host
HEK293
Target
218 linker
Conjugation
Unconjugated
Tag
Rabbit IgG | Rabbit Kappa
Applications
Flow Cytometry (Evaluation of CAR and SCFV containing 218linker on Human cells) .
Stability
● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months after reconstitution. ● 2-8 °C for 12 months after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/218-MY2203.pdf
Species
Rabbit
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