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Human STEAP2 Full Length Protein, Flag Tag (Nanodisc-pro)

This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Product Specifications

Background

This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

This protein carries a flag tag at the C-terminus. The protein has a calculated MW of 57.7 kDa.

Accession Number

Q8NFT2-1

Expression Region

Glu 2 - Met 490

Host

Insect Cells

Target

STEAP2

Conjugation

Unconjugated

Tag

C-Flag

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Purity

90%

Format

Liquid

Buffer

20 mM HEPES, 150 mM NaCl, pH7.5

Additives

Glycerol

Molecular Weight

57.7 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

100ug*1

Host or Source

InsectCells

Species

Human

Protein ID

Q8NFT2-1

Preservative

Glycerol

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