Human AGO1 Protein, His Tag (MALS verified)
AGO1 (Argonaute-1) is a key protein in the RNA interference (RNAi) pathway. As a core component of the RNA-induced silencing complex (RISC), it binds to small non-coding RNAs like microRNAs (miRNAs) and short interfering RNAs (siRNAs) . Unlike its close relative AGO2, AGO1 lacks the slicer activity to cleave target messenger RNAs (mRNAs) . Instead, its primary function is to guide RISC to target mRNAs, leading to translational repression and subsequent mRNA degradation. This makes AGO1 crucial for gene silencing and the post-transcriptional regulation of gene expression.
Product Specifications
Background
Specifications
Accession Number
Q9UL18-1
Expression Region
Glu 2 - Ala 857
Host
Insect Cells
Target
AGO1
Conjugation
Unconjugated
Tag
N-10xHis
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Purity
90%
Format
Liquid
Buffer
PBS, pH7.4
Additives
Glycerol
Molecular Weight
99.1 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
100ug*1
Host or Source
InsectCells
Species
Human
Protein ID
Q9UL18-1
Preservative
Glycerol
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