Human SLC7A11 Full Length Protein (VLP)
Human SLC7A11 Full Length Protein (VLP) (SLS-H52P5) is expressed from human 293 cells (HEK293) . It contains AA Val 2 - Leu 501 (Accession # Q9UPY5) .
Product Specifications
Background
Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the tripeptide glutathione (GSH) . A rate limiting step in cellular GSH synthesis is the availability of cysteine. However, circulating cysteine exists in the blood as the oxidised di-peptide cystine, requiring specialised transport systems for its import into the cell. System xc- is a dedicated cystine transporter, importing cystine in exchange for intracellular glutamate. To counteract elevated levels of reactive oxygen species in cancerous cells system xc- is frequently upregulated, making it an attractive target for anticancer therapies.
Specifications
This protein .
Accession Number
Q9UPY5
Expression Region
Val 2 - Leu 501
Host
HEK293
Target
SLC7A11
Conjugation
Unconjugated
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 12 months under sterile conditions.
Endotoxin
1.0 EU per μg
Format
Liquid
Buffer
PBS, Arginine, pH7.4
Additives
Trehalose
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/SLS-H52P5.pdf
Species
Human
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