GMP Human Truncated Vitronectin / VTN-N Protein
Vitronectin is also known as S-protein, VN, VTN, V75. Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and migration, wound healing, and tissue remodeling. The primary cellular source of vitronectin is hepatocytes. Blocking of Hic (a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Product Specifications
Background
Specifications
Accession Number
P04004
Expression Region
Val 62 - Leu 478
Host
E. coli
Target
Vitronectin
Conjugation
Unconjugated
Tag
Native
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 5 years under sterile conditions.
Endotoxin
10 EU/mg
Purity
95%
Format
Liquid
Buffer
PBS, 0.15 M Arginine, 0.5 mM EDTA, 250 mM N-Acetyl-L-cysteine, pH7.4
Molecular Weight
47.6 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
1mg*5
Host or Source
E. coli
Species
Human
Protein ID
P04004
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