Cynomolgus IL-31 Protein, His Tag, Ultra Low Endotoxin (MALS verified)
IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
Product Specifications
Background
Specifications
Accession Number
G7PJ78-1
Expression Region
Leu 27 - Thr 163
Host
HEK293
Target
IL-31
Conjugation
Unconjugated
Tag
N-10xHis
Stability
Endotoxin
0.0005 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
17.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Host or Source
HEK293
Species
Cynomolgus
Protein ID
G7PJ78-1
Preservative
Trehalose
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Insulin (2D11-H5), CF640R conjugate, 0.1mg/mL
Cytokeratin 17 (E3), CF594 conjugate, 0.1mg/mL
CD50 / ICAM3 (CG106), CF488A conjugate, 0.1mg/mL
