Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human Cadherin-17 / CDH17 Protein, Fc Tag (Active, MALS verified)

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Product Specifications

Background

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 111.4 kDa. The protein migrates as 120-140 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q12864-1

Expression Region

Gln 23 - Met 787

Host

HEK293

Target

Cadherin-17

Conjugation

Unconjugated

Tag

C-Fc

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

20 mM Tris, 150 mM NaCl, pH8.0

Additives

Trehalose

Molecular Weight

111.4 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

Q12864-1

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MMP9 Monoclonal Antibody
BT-MCA4714-01 50 µL

MMP9 Monoclonal Antibody

Ask
View Details
MMP9 Monoclonal Antibody
BT-MCA4714-02 100 µL

MMP9 Monoclonal Antibody

Ask
View Details
Sheep Peroxisome Assembly Factor 2 (PEX6) ELISA Kit
MBS9932420-01 48 Well

Sheep Peroxisome Assembly Factor 2 (PEX6) ELISA Kit

Ask
View Details
Sheep Peroxisome Assembly Factor 2 (PEX6) ELISA Kit
MBS9932420-02 96 Well

Sheep Peroxisome Assembly Factor 2 (PEX6) ELISA Kit

Ask
View Details
Sheep Peroxisome Assembly Factor 2 (PEX6) ELISA Kit
MBS9932420-03 5x 96 Well

Sheep Peroxisome Assembly Factor 2 (PEX6) ELISA Kit

Ask
View Details
Sheep Peroxisome Assembly Factor 2 (PEX6) ELISA Kit
MBS9932420-04 10x 96 Well

Sheep Peroxisome Assembly Factor 2 (PEX6) ELISA Kit

Ask
View Details