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PE-Labeled Monoclonal Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) (0.03% Proclin)

Monoclonal Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) is a mouse monoclonal antibody produced from hybridoma.

Product Specifications

Background

T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1, which is phosphorylated on tyrosine residues by LYN, so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development, selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.

Target

CD5

Conjugation

PE Labeled

Tag

Mouse IgG1 | Mouse kappa

Applications

Flow Cytometry (Evaluation of the expression of CD5 on Human cells) .

Stability

Store at 2-8 °C for 12 months. Please protect from light and avoid repeated freeze-thaw cycles.

Format

Liquid

Buffer

PBS, pH7.4, 0.03% Proclin300, 0.2% BSA

Additives

Trehalose

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Blue ice

Storage Conditions

2-8°C, avoid light

Package Size

50tests*1

Species

Mouse

Preservative

Trehalose

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