Aerothionin
Product Specifications
UNSPSC Description
Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs)[1][2].
Target Antigen
Antibiotic; Bacterial; Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/aerothionin.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@]2(C=C(C(OC)=C1Br)Br)CC(C(NCCCCNC(C3=NO[C@@]4([C@H](C(Br)=C(C(Br)=C4)OC)O)C3)=O)=O)=NO2
Molecular Weight
818.10
References & Citations
[1]Drechsel A, et al., Anti-Tumor Activity vs. Normal Cell Toxicity: Therapeutic Potential of the Bromotyrosines Aerothionin and Homoaerothionin In Vitro. Mar Drugs. 2020 May 1;18(5):236.|[2]Šimovičová M. Synthesis of aerothionin analogs as potential antimycobacterial agents[J]. 2021.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121349/Aerothionin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121349/
Clinical Information
No Development Reported
CAS Number
28714-26-3
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