Purified Anti-Human CD22 Antibody[HIB22]
This is a Purified Anti-Human CD22 [HIB22] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup) . CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.
Synonyms
B-cell receptor CD22, Cd22, B-lymphocyte cell adhesion molecule, BL-CAM, Sialic acid-binding Ig-like lectin 2, Siglec-2, T-cell surface antigen Leu-14, CD22, Lyb-8, Siglec2
Gene ID
933
Reactivity
Human
Conjugation
Unconjugated
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
0.5 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage Conditions
This product can be stored at 2-8°C for 12 months. Do not freeze.
Host or Source
Mouse
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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