AF647 Anti-Human CD193/CCR3 Antibody[5E8]
This is a AF647 Anti-Human CD193/CCR3 [5E8] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+?hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
Synonyms
CC CKR3, MIP1-alpha receptor like-2, eotaxin receptor, CCR, C-C chemokine receptor type 3
Gene ID
1232
Reactivity
Human
Conjugation
AF647
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
Host or Source
Mouse
Isotype
Mouse IgG2b, κ
Available Sizes
Curated Selection
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