AF647 Anti-Mouse CD163 Antibody[S15049F]
This is a AF647 Anti-Mouse CD163 [S15049F] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced) /155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
Synonyms
M130, MM130, SCARI1
Gene ID
93671
Reactivity
Mouse
Conjugation
AF647
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
0.5 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
Host or Source
Rat
Isotype
Rat IgG2a, κ
Available Sizes
Frequently Asked Questions
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