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APC Anti-Mouse CD163 Antibody[S15049F]

This is a APC Anti-Mouse CD163 [S15049F] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced) /155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Synonyms

M130, MM130, SCARI1

Gene ID

93671

Reactivity

Mouse

Conjugation

APC

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Host or Source

Rat

Isotype

Rat IgG2a, κ

Available Sizes

Curated Selection

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