PE Anti-Human CD8a Antibody[HIT8a]
This is a PE Anti-Human CD8a [HIT8a] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers) . CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3?domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Synonyms
T-cell surface glycoprotein CD8 alpha chain, CD8A, T8, Leu2, MAL
Gene ID
925
Reactivity
Human
Conjugation
PE
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
Host or Source
Mouse
Isotype
Mouse IgG1, κ
Available Sizes
Frequently Asked Questions
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