FITC Anti-Mouse CD200/OX2 Antibody[OX-90]
This is a FITC Anti-Mouse CD200/OX2 [OX-90] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, ?B cells, ?and brain tissue (neurons) ; but not on NK cells, granulocytes, monocytes, or macrophages.? CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues.? CD200 is the ligand for CD200 receptor (CD200R) .? The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity.? Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.
Synonyms
OX-2 membrane glycoprotein, OX-2, MRC
Gene ID
4345
Reactivity
Mouse
Conjugation
FITC
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
0.5 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
Host or Source
Rat
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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