AF647 Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]
This is a AF647 Anti-Mouse CD150/SLAM [TC15-12F12.2] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.
Synonyms
Slam, Slamf1, CD 150, Signaling lymphocytic activation molecule
Gene ID
27218
Reactivity
Mouse
Conjugation
AF647
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
Host or Source
Rat
Isotype
Rat IgG2a, λ
Available Sizes
Curated Selection
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