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AFViolet 450 Anti-Human CD61 Antibody[VI-PL2]

This is a AFViolet 450 Anti-Human CD61 [VI-PL2] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.

Synonyms

GP3A, GPIIIa, ITGB3, Integrin beta-3

Gene ID

3690

Reactivity

Human

Conjugation

AFViolet 450

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Host or Source

Mouse

Isotype

Mouse IgG1, κ

Available Sizes

Curated Selection

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