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AFRed 780 Anti-Human CD86 Antibody[BU63]

This is a AFRed 780 Anti-Human CD86 [BU63] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4) . CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Synonyms

T-lymphocyte activation antigen CD86, Cd86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1

Gene ID

942

Reactivity

Human

Conjugation

AFRed 780

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Host or Source

Mouse

Isotype

Mouse IgG1, κ

Available Sizes

Frequently Asked Questions

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